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논문검색

Crystal Structure Theory and Applications of 14-Ethoxy-4,6,-dimethyl-8.12-dioxa-4.6-diazatetracyclo [8.8.0.02,7.013,18]octadeca-13,15,17-triene-3,5-dione

초록

영어

In view of the growing medicinal importance of chromene and its derivatives, the single crystal X-ray diffraction study was carried out for the potential active 4,6-dimethyl-9-phenyl-8,12-dioxa-4,6-diazatetracyclo [8.8.0.02,7.013,18] octadeca- 2(7),13,15,17-tetraene-3,5,11-trione-2-ethoxyphenyl (2E)-but-2-enoate (C18H20N2O5). In the title compound are two molecules exist in the asymmetric unit. It crystallizes in the monoclinic space group P21/c with unit cell dimension a=14.608(3) Å, b=12.845(3) and c= 17.781(4) [alpha & gamma=90o beta=91.233(5)o]. Both pyran and pyran ring of the chromene moiety adopts sofa conformation in the molecule A & B. The crystal structure is stabilized by intramolecular C-H...O hydrogen bond interaction.

목차

Abstract
 1. Introduction
 2. Material and Methods
 3. Experimental
  3.1. Synthesis of the Title Compound
  3.2. X-Ray Crystallography
 4. Results and Discussion
 5. Conclusion
 Acknowledgement
 References

저자정보

  • Jagadeesan Ganapathy Department of Physics, Presidency College, Chennai 600005, India
  • Sivakumar. G Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai-600025, India
  • Bakthadoss Manickam Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai-600025, India
  • Aravindhan Sanmargam Department of Physics, Presidency College, Chennai 600005, India

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