earticle

영어

Hematopoietic stem cell transplantaion(HSCT) has been used to treat a variety of non-malignant and malignant lymphohematopoietic disease. It was reported that performance status(ECOG PS) is associated with nutritional status which is most affective factor for treatment and recovery in cancer patients, and ECOG PS is also independent prognostic factor in patients. This study investigated that the effects of ECOG PS on body composition, nutritional indices and bone metabolism before and after a year post-HSCT. Reports of 44 patients undergoing HSCT were analysed in this study. According to their performance status before and after a year post-HSCT, patients were divided into a improved(or maintained) group A(n=28) and a decreased group B(n=16). Body fat ratio and waist hip circumference of group B were higer than group A(p<.05). Hemoglobin concentration increased after HSCT in group A(p<.05). Alkaline phosphatase was higher in group A than group B(p<.05). The results indicate that decreased ECOG PS related with high body fat ratio and waist hip circumference, and maintaining ECOG PS contribute to increase of blood hemoglobin level. Further research is needed for intervention to improve ECOG PS intervention.