earticle

영어

Based on myosin heavy chain (MHC) isoform, human skeletal muscle fi-bers can be categorized into three fiber types, type I, IIa, IIx fibers, and each fiber type has different characteristics. Typical characteristics are difference in force production, shortening velocity, and fatigue resis-tance. When the muscle is contract and stretched by a force that is greater than the force generated by the muscle, contraction-induced muscle damage frequently occurs. Several experimental models involv-ing both human and animal have considered the susceptibility of differ-ent muscle fiber type and part of muscles to eccentric induced muscle damage. General consensus is a greater susceptibility of fast-twitch fi-ber or type II fiber to damage following eccentric contractions. However, the results from these previous efforts were not enough to conclude the susceptibility between each individual fiber types after eccentric con- traction. Therefore, the purpose of this review is to explore detail limita-tion and interpretation of previous studies, and review the recent study that eliminated the prior limitations, such as strain magnitude, lengthen-ing velocity, fiber type heterogeneity, and muscle architecture issue.