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Purpose: This study aims to determine the association between psychosocial work environment and self-ratedhealth among general hospital nurses. Methods: A total of 195 nurses working in one general hospital were eligiblefor data analysis by multivariate logistic regression. The psychosocial work environment was measured with theKorean version of the Copenhagen Psycosocial Questionnaire version II (COPSOQ-K). Self-rated health was recodedas good (excellent/good) and not good (fair/poor/bad) to the question, “In general, how would you rate yourhealth status?” Results: 40% of nurses rated their health positively. Commitment to the workplace (OR=1.27),predictability (OR=1.32), recognition and reward (OR=1.41), role clarity (OR=1.32), and social support from colleagues(OR=1.25) were positively associated with self-rated health of nurse participants. Work-family conflict(OR=0.82) was negatively associated with self-rated health. Conclusion: The findings suggest that psychologicalwork environment predicts self-rated health of hospital nurses. Good psychological work environment may behelpful in improvement of nurses’ health.