earticle

영어

This study was carried out to evaluate the efficacy of cosmetics manufactured with retinol, hyaluronic acid and defined cell culture media 4 (DCCM4) on facial skin care. All testing cosmetics were raised to hyaluronic acid, β-glucan, by 0.2% in the same addition. Also we prepared three kinds of testing cosmetics. Distilled water was used as solvent of ingredients in hyaluronic acid testing cosmetics, retinyl palmitate were added to hyaluronic acid testing cosmetics to 10,000 IU/g for retinol testing cosmetics, and DCCM4 was used as solvent of ingredient in DCCM4 testing cosmetics. To achieve evaluation of efficacy, 30% glycolic acid peeling was applied to facial skin of 32 study participants once a week during 4 weeks. By home care, the skin conditions were measured for the analysis of wrinkle, pigmentation, moisture and skin tone before and after treatment after applying it 84 times twice a day for 6 weeks. In the change of facial skin between 32 study participants, the moisture increased, but no significant difference among study group. For the wrinkle, DCCM4 was in great decrease below and around their eyes, which there was a significant difference (p<.01). For the pigmentation by polarized light, DCCM4 was in great decrease on their nose and cheeks, below and around their eyes, which there was a significant difference (p<.05, p<.01, and p<.001). For the pigmentation by ultraviolet light, DCCM4 was in great decrease on their forehead and cheeks, below and around their eyes, which there was a significant difference (p<.05, p<.01, and p<.001). For the skin tone, DCCM4 was in great increase on their forehead, nose and cheeks, below their eyes more than retinol and HA, which there was a significant difference (p<.01). As a consequence, cosmetics manufactured with DCCM4 can be used for improving skin aging, and it is expected to carry out more systematic and effective studies in the future.