원문정보
The Recent Trend of Percutaneous Absorption Used in Cosmetics
초록
영어
The formidable barrier property of the stratum cornemum and the high hydrophilicity of active ingredientmake it difficult to permeate through the skin and reach to its site of action. So the interest of cosmeticindustry is how to promote percutaneous absorption of active ingredients. The aim of this study wasto analysis and organize theses on percutaneous absorption of active ingredient. Physical penetrationenhancers on the skin permeation is iontophoresis, electroporation, sonophoresis, tape stripping, and soon. A physical penetration enhancer that has received greater attention lately is MTS (Microneedle TherapySystem). This therapy uses micro-needle which is equipped with very thin, delicate needles smaller than a0.07 mm thick hair. During this therapy, the micro-needle makes small holes and helps absorb the solutioninto the skin. But the penetration enhancers on the skin permeation that has received the greatest attentionsince 2005 is a hoof shape method, such as pH-responsive P (MAA-co-PEGMA) hydrogel, micelle, nanoemulsion, liposome, ethosome. Especially, theses on nano emulsion and liposome (including ethosome)hold a large majority. According to the theses, the ethosome exhibited more enhanced skin permeabilitythan general liposome and ethanol solution.
목차
Ⅰ. 서론
Ⅱ. 본론
1. 경피흡수 원리 및 경로
2. 경피 흡수 촉진에 영향을 주는 일반적인 요인들
3. 물리적 접근법
4. 제형적 접근법
Ⅲ. 결론
참고문헌