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Purpose: The purpose of this study was to evaluate the effectiveness of the 3-step health education and tele-coaching program for the disabilities with hypertension in rural regions. Method: The interrupted time series/quasi-experimental study of one group was conducted for 15 months at the rural community health center. The 3-step health education and tele-coaching program was given to participants during 15months. Results: There were significant changes in self–management (F = 3.406, p < .01) and preferred salt concentration (F = 6.388, p < .001) between baseline assessment and other time points. No significant changes in systolic and diastolic blood pressure were found between each time point and these physiological indicators were within a normal range over time. Conclusion: The tailored program for disabled people with hypertension is very effective in improving health-related behaviors regarding salt restriction and self-management of hypertension.