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Objectives: This study examined the factors affecting the quality of life relating to oralhealth using OHIP-14 of college students. Also, this was to help college students toenhance their oral health. Methods: A Total of 334 self-administered questionnaires were collected from university student in Cheon -an. The statistical methods used for data analysis were the descriptive statistics, Independent samples t -test, One-way ANOVA, correlation analysis, multiple linear regression analysis. Results: First, A month pocket money and coffee consumption were significantlyrelated to functional and physical Oral health foctor. Second, A month pocket money and coffee consumption were significantly related to Mental and social Oral health foctor. Finally, multiple linear regression analysis showed that a month pocket money, coffee consumption have a negative effect on the quality of life relating to oral health, Whereas an experience of oral health education a positive effect on this. Conclusion: Oral health related quality of life should be improved by investigating thefactors affecting oral health and thus developing the program enhancing the oral health to prevent oral disease. In addition, in order to health promotion physical, mental, social, including the oral health, program development and research incessant must be carried out.