earticle

영어

In recent years, illegal acts for evasion of military service have been attempted by applying scopolamine, commercial drug patch (Kimite ) for motion sickness, on the pupils at the physical examination for draft, which induce a pupillary dilatation. Therefore, the cotton wool soaked with cleansing solution of eyeball in suspected candidates has been referred to the NFS to hunt offender. We analyzed nine cases of cotton wool soaked with cleansing solution of eyeball for the detection of scopolamine, main constituent of Kimite . UPLC-Hybrid QTrap-MS/MS could detect trace amount of scopolamine because requested samples are cleansing solution of eyeball, not vitreous humor, blood or urine. One case of nine samples was tested positive, 30.0 pg of scopolamine, with 1 pg of limit of detection, 5 pg of limit of quantitation. In conclusion, our analytic method could, quickly and accurately, evaluate the illegal attempts for applying Kimite on eyeball to avoid the military duty, which may be useful in other institutes.