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Objectives: This study was conducted in order to analyze the effect of drinking and smoking on family relationship satisfaction and life satisfaction. Methods: The 7th Korea Welfare Panel data were utilized and 1270 subjects from the baby boom generation (1955-1963) were included in this study. SPSS 18.0 and AMOS 18.0 were used for data analysis. Results: The results were as follows;First, smoking was found to affect life satisfaction negatively and smoking decreased family relationship satisfaction and life satisfaction. Second, the impact of alcohol consumption on life satisfaction was not significant. Third, we found that smoking had a direct impact on life satisfaction, as well as family relationship satisfaction, and an indirect influence on life satisfaction through family relationship satisfaction. Conclusion: Smoking not only affected health but also life satisfaction. Therefore, smoking policy should be approached using an integrated method.