국내 노인 심부전 환자에서의 잠재적으로 부적절한 약물사용 현황에 대한 연구


Assessment of Potentially Inappropriate Medication Use in Korean Elderly Patients with Chronic Heart Failure

배민경, 이인향, 윤정현

피인용수 : 0(자료제공 : 네이버학술정보)



Purpose: The purpose of the present study was to assess the incidence of the potentially inappropriate medication (PIM) use in Korean elderly patients with heart failure, and to evaluate factors that influence PIM use. Method: Korean National Health Insurance claims database between January 2009 and December 2009 was used. Using 2012 updated Beers criteria, PIM use in heart failure patients aged 65 years or older was examined. Result: The incidence of PIM use in elderly heart failure patients was higher than in overall elderly patients. Among the 12,759 elderly patients with heart failure, 46.2% of study subjects were prescribed PIM(s) at least once. The number of PIM per 10 medications that patients received per patient was 1.53. The most commonly used PIMs in elderly heart failure patients were benzodiazepines (30.9%), non-steroidal anti-inflammatory drugs (NSAIDs) including COX-2 inhibitors (16.3%), digoxin (9.9%), and spironolactone (9.0%). Women (odds ratio, 1.20; 95% CI, 1.17-1.24), medical aid (odds ratio, 1.11; 95% CI, 1.08- 1.13), and long-term facilities (odds ratio, 2.69; 95% CI, 2.44-2.96) were revealed to be important factors associated with PIM use. In addition, patient’s age also seems to influence PIM use. Conclusion: Elderly heart failure patients are at a greater risk for adverse drug events attributed by inappropriate medication use. Efforts to increase awareness of PIM use in elderly heart failure patients are needed. In addition, various comprehensive strategies and policies to identify and prevent PIM use should be established nationwide.


 연구 방법
  연구 대상약물
  변수의 정의
 연구 결과
  연구대상의 특징
  Beers Criteria에 의한 PIM 사용현황 분석
 감사의 글


  • 배민경 Min Kyung Bae. 부산대학교 약학대학
  • 이인향 Iyn-Hyang Lee. 영남대학교 약학대학
  • 윤정현 Jeong-Hyun Yoon. 부산대학교 약학대학


자료제공 : 네이버학술정보

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