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Although the ageing process is poorly understood, scientists do know that it is caused by many factors. There is some evidence that telomere erosion contributes to age-associated human pathology. However, it is definitely not the only, or even dominant cause, although it has been proven that ageing was accelerated in mice engineered to lack in telomerase. Other factors such as highly reactive particles called free radicals which are made naturally in the body cause damage to cells, as well as smoking, ultraviolet light, and other environmental factors. Another concern of telomerase reactivation is that it is a hallmark of most human cancers. Despite such revolutional discoveries, the obstacles we must overcome in order to find the key to rejuvenation are almost overwhelming, but through our effort, they may be surmountable.