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논문검색

Concentration Calibration of Urine Biomarkers for Diagnosis Improvement of Ovarian Cancer

원문정보

Eun-Suk Yang, Yu-Seop Kim, Chan-Young Park, Hye-Jeong Song, Jong-Dae Kim

보안공학연구지원센터(IJBSBT) International Journal of Bio-Science and Bio-Technology Vol.6 No.1 2014.01 pp.65-72
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초록

영어

This paper investigates the calibration effect of urine biomarkers by creatinine. The biomarkers were obtained from each urine sample of 256 patients (cancer: 137, benign: 119). The logistic regression of the combinations of 2 biomarkers calibrated by creatinine concentration was compared with that of the 3 biomarkers including creatinine. The average AUC over 1000 rounds of 5-fold cross validations was employed to evaluate the performance. The logistic regression of the calibrated biomarkers showed better performance than that without calibration for the top- ranked combinations.

목차

Abstract
 1. Introduction
 2. Materials and Methods
  2.1 Data collection
  2.2 Comparison method
 3. Results
 4. Conclusion
 Acknowledgments
 References

키워드

저자정보

  • Eun-Suk Yang Dept. of Ubiquitous Computing, Hallym University, Bio-IT Research Center, Hallym University, 1 Hallymdaehak-gil, Chuncheon, Gangwon-do, 200-702 Korea
  • Yu-Seop Kim Dept. of Ubiquitous Computing, Hallym University, Bio-IT Research Center, Hallym University, 1 Hallymdaehak-gil, Chuncheon, Gangwon-do, 200-702 Korea
  • Chan-Young Park Dept. of Ubiquitous Computing, Hallym University, Bio-IT Research Center, Hallym University, 1 Hallymdaehak-gil, Chuncheon, Gangwon-do, 200-702 Korea
  • Hye-Jeong Song Dept. of Ubiquitous Computing, Hallym University, Bio-IT Research Center, Hallym University, 1 Hallymdaehak-gil, Chuncheon, Gangwon-do, 200-702 Korea
  • Jong-Dae Kim Dept. of Ubiquitous Computing, Hallym University, Bio-IT Research Center, Hallym University, 1 Hallymdaehak-gil, Chuncheon, Gangwon-do, 200-702 Korea

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