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논문검색

Derivation of a Closed-Form Equation Describing the Magnetophoretic Velocity of Superparamagnetic Microbeads in Microfluidic Channels under the Influence of an External Magnetic Field

초록

영어

The object of this research paper is to obtain an analytical function that describes the dynamics of motion of superparamagnetic beads in a microfluidic channel filled with a liquid such as water or blood under the influence of an external magnetic field. A closed-form equation was derived from first principles and then simulated using MATLAB® and the results compared to those obtained experimentally by other researchers. This equation is an adequate tool to calculate the arrival times of functionalized magnetic beads of different radii at sensor location which might be useful in biomicrofluidics applications, specifically those that fall in the category of Lab-On-A-Chip in which segregation of bound and unbound beads could be determined on the basis of their different speeds without having to use magnetic separation and further external processing with additional instruments. Additionally, a practical design equation was developed to calculate the operating point of a commercial electromagnet to obtain desired speeds at predetermined distances from the magnet’s surface.

목차

Abstract
 1. Introduction
 2. Derivation of the Equation
 3. Verification with Experimental Results
 4. Design Example Using a Commercial Electromagnet
 5. Conclusions
 References

저자정보

  • Paul Gomez Quantum Nanoelectronics, Inc, Fort Lauderdale, Florida, USA
  • Ewa Wojcikiewicz Florida Atlantic University, College of Medicine, Boca Raton, Florida, USA
  • Claudia Lopez Quantum Nanoelectronics, Inc, Fort Lauderdale, Florida, USA

참고문헌

자료제공 : 네이버학술정보
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