earticle

영어

The object of this research paper is to obtain an analytical function that describes the dynamics of motion of superparamagnetic beads in a microfluidic channel filled with a liquid such as water or blood under the influence of an external magnetic field. A closed-form equation was derived from first principles and then simulated using MATLAB® and the results compared to those obtained experimentally by other researchers. This equation is an adequate tool to calculate the arrival times of functionalized magnetic beads of different radii at sensor location which might be useful in biomicrofluidics applications, specifically those that fall in the category of Lab-On-A-Chip in which segregation of bound and unbound beads could be determined on the basis of their different speeds without having to use magnetic separation and further external processing with additional instruments. Additionally, a practical design equation was developed to calculate the operating point of a commercial electromagnet to obtain desired speeds at predetermined distances from the magnet’s surface.