earticle

영어

Korean ginseng (Panax ginseng C.A. Meyer) is one of the most widely used medicinal herbs in the world. Although multiple biological activities of Korean ginseng have been widely studied, anti-oxidant property and moisturizing effect of oil exracted from Korean red ginseng (KRO) remains unknown. Here in vitro anti- oxidant activity and the moisturizing effect in 20-30 aged female of KRO were investigated. The peroxyl radicals are dose-dependently and significantly scavenged by KRO between 0.01-0.1% as judged by ORAC and its electron donating capacity was examined through reduction potential using copper ions. The KRO showed dose-dependent increasing reduction capacity between 0.01% and 0.1%. In addition, the KRO effectively attenuated AAPH- or Cu2+- induced oxidative stress in HepG2 cells. We further investigated the moisturizing effect of KRO in 20-30 aged female for 2 weeks. The treatment of moisturizer with KRO improved moisture content of skin in 20-30 aged female (n=4). These results imply that the KRO may be utilized as strategy for skin. In addition, our findings provide the scientific evidences for the development of skin targeted nutricosmetics and cosmetics.