원문정보
Functional Characterization of Callus Extracts of Apple ‘Hirosaki’ for Cosmetic Materials
초록
영어
In order to investigate functional characterization of callus extracts of apple ‘Hirosaki’ for cosmetic materials, biological activities of its extracts including wrinkle improvement, hair growth, and anti-inflammatory effect were investigated. The callus extract showed similar activity with TGF-β used as positive control at 50 μg/mL in the test of collagen synthesis, and increased 40% of proliferation of hair follicle dermal papilla cells. Especially, in case of anti-inflammatory effect, callus extract inhibited about 50% of COX-2 expression which was known as response for intermediating inflammation, and about 70% of eotaxin-1 production which was increased by atopy dermatitis.
목차
1. 서론
2. 재료 및 방법
2.1. 실험재료
2.2. 시료 추출
2.3. 콜라겐 생합성 증진 활성 분석
2.4. 세포생존력 분석
2.5. 모유두 세포 증식 활성 활성 분석
2.6. Cyclooxgenase-2 (COX-2) 저해 측정
2.7. Eotaxin-1 저해 측정
2.8. 통계처리
3. 결과 및 고찰
3.1. 콜라겐 생합성 증진 활성
3.2. 모유두 세포 증식 활성
3.3. Cyclooxgenase-2 (COX-2) 저해
3.4. Eotaxin-1 저해
4. 결론
사사
REFERENCES