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This paper is concerned with formulating the design specification and making hyperbaric oxygen chamber for multi-users. HBOT(Hyperbaric Oxygen Therapy) is very effective remedy for increasing the concentration of melted oxygen in human and animal body. The melted oxygen supplies to each cell in body to recover the normal condition. This research reported the design specifications and mechanical test results of hyperbaric oxygen chamber made with polyurethane as well as computational analysis with CATIA program. These data can set the physical dimensions of practical HBOT equipment for multi-users and be used to produce the effective commercial model.