earticle

영어

Bacteria produce biofilm in nature. The physiology of bacteria in biofilm is different from in planktonic growth, such as more resistant to antibacterial agents (1). Minimizing the biofilm formation of bacteria reduces the change to get bacterial problems (2, 3). We evaluated the inhibitory effect of four oriental herbs on biofilm formation of Yersinia enterocolitica, a human pathogenic Gram negative bacteria, Xanthomonas oryzae, a rice pathogenic Gram negative bacteria, and Streptococcus mutans, a common Gram positive bacteria in human mouth. The water extracts of Rheum palmatum with 14.17 g/L reduced 73%, 37%, and 78% of biofilm formation of S. mutans, Y. enterocolitica, and X. oryzae, respectively. The dichloromethane extracts of Angelica gigas with 7.88 g/L, the ethyl acetate extracts of Angelica gigas with 4.25 g/L, the butanol extracts of Aucklandia lappa with 7.60 g/L, and the ethyl acetate extracts of Myristica fragrans with 0.95 g/L inhibited the biofilm formation of Y. enterocolitica and X. oryzae mostly. The tested oriental herbs can be used for the methods to control the bacterial biofilm formation in many industries of food, pharmaceuticals, and more.