원문정보
초록
영어
Bacteria have evolved to survive in the environment of the oral cavity. Recent technical advances have led to resonable conclusion that dental plaque is a biofilm. Biofilms are masses of microorganisms that bind to and multiply on a solid surface, typically with a fluid bathing mucosal microbes. The precursor of biofilm is complex and closely linked with the oral cavity’s overall dynamic environment that undergoes rapid changes in pH, nutrient availability and oxygen tension. Therefore, the control of oral biofilm is expected to be prevent dental decay and cavities. This study was aimed to test the inhibition activity of plant extracts against biofilm formation. Seven extracts showed a meaningful extent in inhibition of biofilm or related enzyme glucosyltransferase (GTase). Further study on the mechanism of inhibition and responsible chemical(s) will shed light on the cause of related dental diseases.