earticle

영어

Cosmetic activities of the Curcuma longa Linne leaf was not much studied yet even though the Curcuma longa Linne roots was well investigated as a source of Curcumin. In this work, cosmetic activities of the Curcuma longa Linne leaf were compared according to different drying methods: conventional hot air drying, freeze drying and low vacuum pressure drying. The highest extraction yield of 29.4% was obtained from freeze drying process, whose value was very close to 29.2% from low vacuum drying process. However, relatively lower extraction yield were observed as 24.5% and 25.3 from the non-dried leaf as control and hot air drying process. The lowest cytotoxicity against CCD-986sk was observed as 15.4% and followed by 16.3% from freeze drying. The extracts from vacuum drying and conventional hot air drying processes were also measured as 22.3% and 29.2%, respectively. Relatively high cytotoxicity against mormal human cell line was observed from hot air drying process possibly by the formations and/or easy release of toxic residues. The SEM observation of dried leaves was also made to compare the morphological changes from each drying process, which can also tell why the extracts from vacuum drying method showed better extraction yield and cosmetic activities. It was found that higher cytotoxicity was closely related to serveral cosmetic activities such as tyrosinase and melatonin inhibition activities by showing much better cosmetic activities of the extracts from both freeze and vacuum drying processes than those from the control and got-air drying such as 32.1% and 33.5% vs 40.1% and 45.3% for tyrosinase inhibition in adding 1.0 mg/ml of the extracts, and 15.4% and 24.2% vs 33.8% for melanin inhibition. It was interesting that there was not much differences between cosmetic activities and cytotoxicity of the extracts from freeze and vacuum drying processes.