earticle

영어

Gold nanoparticles have garnered much attention from chemical and biological societies due to their unique size- and shape- dependent optical property.[1] These properties render them useful materials in various applications, ranging from bio-imaging, and bio-sensing to chemical catalysis. For the succuss of these applications, it is important to synthesize the well-controlled size- and shape- gold nanoparticles.[2,3] During the past decades, wet-chemical synthesis methods have been used to prepare the gold nanoparticles. However, this method suffers from some drawbacks: highly labor intensive and time consuming due to numerous manual steps, resulting in the difficulties for finding the optimized condition of the desired nanoparticles. To address these issues, we have developed a centrifugal microsystem to synthesize 30 different gold nanocrystals on each different condition at the same time. The microsystem consists of bottom layer and upper layer. In the bottom layer, we designed 30 identical unit which has three reservoirs for a seed solution, a growth solution and a control solution connected with different dimensional microfluidic channels. In the upper layer, there are two channels for seed and growth solutions which are conntected with seed and grwoth solution reservoir in the bottom layer through via holes. By controlling RPM, we could dispense the seed solution, the growth solution, and the control solution successively, so that gold nanoparticles was synthesized on the thirty different reaction condition simultaneously. Such a novel centrifugal microdevice simplifies the complicated synthesis procedure and play an important role in optimizing the condition for synthesizing the desired gold nanoparticles.