earticle

영어

In this study, the 4-aminothiophenol (ATP)/gold nanodot modified electrode was fabricated for determination of purine bases. First, gold nanodot patterned ITO electrode was fabricated by thermal evaporation through polystyrene bead monolayer. Then, poly-ATP was polymerized on ITO surface by electrochemical method. After finishing fabrication of modified electrode, electrochemical property of adenine and guanine mixture was detected by differential pulse voltammetry. The results showed linear relation between concentrations and oxidation current peaks of both adenine and guanine. Therefore, our newly developed modified electrode could be suggested to high sensitivity simultaneous detection of purine bases in the related physiology process. Acknowledgements: This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MEST)(2012-0000163), by The Nano/Bio Science & Technology Program (M10536090001-05N3609-00110) of the Ministry of Education, Science and Technology (MEST) and by the Original Technology Research Program for Brain Science through the NRF funded by the MEST.(2012-0006592)