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논문검색

Cell culturing on the partially oxygen and fluorine terminaterd graphene sheet

원문정보

Hong-Gi OH, Hyo-Geun NAM, Da-Ae JO, Hye-Bin PARK, Kwang-Hwan JHEE, Si-Hyung KIM, Dae-Hoon KIM, Min-Hye KIM, Chang-Man KIM, Kwang-Soup SONG

한국생물공학회 한국생물공학회 학술대회 2013 춘계학술대회 2013.04 pp.299-299
피인용수 : 0건 (자료제공 : 네이버학술정보)

초록

영어

Recently, the approaches of biosensor and bioengineering combine with various nanomaterials to find suitable material in biosicence. Especially, carbon-based nanomaterials are considered to be one of the key element in nanotechnology and biotechnology. The graphene is a single atom sheet of sp2 bonded carbon atoms in a closely packed honeycomb structure with unique physical, chemical and mechanical properties. The biological application of graphene still remains unexplored and wide-open.In this work, we use graphene sheet that surface is treated by plasma in oxygen (O2) and fluorine (C3F8) gas environment. We investigate the cell culture conditions using human nerve cell line (SH-SY5Y) which are exposed to plasma treated graphene onto polyethylene terephthalate (PET). As a result, we confirm that the difference of the characteristics of cell growth depending on the surface treatment by of hydrophilic (-O) and hydrophobic (-F). In addition, we show the reaction of the nerve cells according to the electrical stress on graphene sheet[2]. In order to evaluate the cell viability and morphology, we check the MTT assay and optical microscopy images. We support that the potential of graphene as a material for neural interfacing and provides insight into the future biomedical applications.

키워드

저자정보

  • Hong-Gi OH Dept. of Medical IT Convergence Engineering, Kumoh National Institute of Technology, Gumi, 730-701.
  • Hyo-Geun NAM Dept. of Medical IT Convergence Engineering, Kumoh National Institute of Technology, Gumi, 730-701.
  • Da-Ae JO Dept. of Applied Chemistry, Kumoh National Institute of Technology, Gumi, 730-701.
  • Hye-Bin PARK Dept. of Applied Chemistry, Kumoh National Institute of Technology, Gumi, 730-701.
  • Kwang-Hwan JHEE Dept. of Applied Chemistry, Kumoh National Institute of Technology, Gumi, 730-701.
  • Si-Hyung KIM Dept. of Medical IT Convergence Engineering, Kumoh National Institute of Technology, Gumi, 730-701.
  • Dae-Hoon KIM Dept. of Medical IT Convergence Engineering, Kumoh National Institute of Technology, Gumi, 730-701.
  • Min-Hye KIM Min-Hye KIM,\. Dept. of Medical IT Convergence Engineering, Kumoh National Institute of Technology, Gumi, 730-701.
  • Chang-Man KIM Gumi electronics & Information Technology Research Institute, Biomedical IT Convergence Center, Gumi, 730-701.
  • Kwang-Soup SONG Dept. of Medical IT Convergence Engineering, Kumoh National Institute of Technology, Gumi, 730-701.

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