원문정보
초록
영어
Generally speaking in a cell metabolism, higher ratio of NAD+/NADH means more active metabolic condition because NADH is rapidly consumed in several metabolic reactions. Also, when acetoin becomes 2,3-butanediol, NADH turns to NAD+ in the reaction. Since this reaction was added to E. coli W3110 wild type, the mutant’s NAD+/NADH ratio would have higher value than it’s wild type’s, and it turned out to be true. Acknowledgments: This research was supported by the Nuclear R&D program through the National Research Foundation funded by the Ministry of Education, Science and Technology, Korea and by the Human Resources Development of the Korea Institute of Energy Technology Evaluation and Planning(KETEP) grant funded by the Korea government Ministry of Knowledge Economy (No. 20114010203090) and by the Original Technology Research Program for Brain Science through the National Research Foundation of Korea(NRF) funded by the Ministry of Education, Science and Technology (2012-0006592)