원문정보
초록
영어
Hepatocyte Growth Factor (HGF) is known to enhance proliferation and reproduction in several human cell types including gastric system cells. Recent studies demonstrated that HGF can induce the progression of various gastrointestinal diseases. Certain natural remedies have been used to treat above mentioned gastric disease. Among all, octopus is rich in taurine and is recommended to effectively suppress the neutral lipids and cholesterol in the blood and liver detoxification fatigue which is crucial for gastric disease treatment. In this study, we examined the anti-inflammatory effect of Octopus dofleini extract and its main component baicalin on HGF-induced human gastric epithelial AGS cell. All results from above assays confirmed in accordance an effective protection against HGF-induced inflammation and proliferation on gastric cancer cell lines. Therefore, O. dofleini is a promising natural source for bioactive materials to be utilized in order to treat common gastric diseases enhanced by HGF.