earticle

영어

Advanced biofuels that target direct replacement of transportation fuels such as gasoline, diesels, and jet-fuels, have been developed due to rising petroleum costs and environmental concerns. We have focused on the production of jet-fuel precursors from biomass and developed a microbial cell factory that enables to produce the possible candidates of a jet-fuel precursor. Corynebacterium glutamicum, a widely-known industrial bacterium, was engineered by introducing biofuel producing pathway constructed in the BioBrick-formatted expression vector systems. Heterologous target genes were synthetized and optimized to produce a precursor of jet fuel candidates. In addition, the effect of cultivation of C. glutamicum for the jet-fuel production was investigated for the higher-production. A target jet-fuel precursor is further converted to high density jet-fuels via catalytic processes. So, the jet-fuel production platform by engineered C. glutamicum could be useful to biofuels production application. This work was supported by the National Research Foundation of Korea Grant funded by the Korean Government (MEST) (2013, University-Institute cooperation program) and ‘Creative Allied Program (CAP)’ through the Korea Research Council of Fundamental Science and Technology (KRCF) and Korea Institute of Science and Technology (KIST).