earticle

영어

To reduce skin irritation and/or inflammation induced by irritants and/or allergens which may be from environmental factors or cosmetics is one of main issues that most cosmetic companies concern. It has become increasingly important to develop safer cosmetics because most people think that cosmetics are one of daily necessaries regardless of age and gender. We performed this project to develop new cosmetic ingredients from natural origins, which can reduce skin irritation and/or inflammation, and which are useful for sensitive skin, atopic-like skin, and troubled skin. Several in vitro screening methods to evaluate the anti-inflammatory effects of natural ingredients were set up, and the safety and anti-irritancy of screened ingredients were confirmed clinically through skin patch test. We also evaluated skin barrier function of screened ingredients that are expected to prevent from weakening the skin barrier. Finally, screened ingredients were formulated in cosmetic products as active materials. Therefore, it is expected both that we can provide the market with new cosmetics which are useful for sensitive skin, atopic-like skin, and troubled skin, and that the screened ingredients can be formulated to reduce the irritation of paraben-free products or sun-care products which may have a possibility to include irritative ingredients.