원문정보
초록
영어
Recently, nanoparticles have received a great interest in a research field of diagnosis as well as therapeutics. Since nanoparticles possess intrinsic features that are often required for drug delivery system and diagnosis, they have potential as platforms for integrating imaging and therapeutic functions, simultaneously. Especially, molecular imaging with theranostic nanoparticles makes it possible not only to provide useful information for monitoring drug delivery, drug release, and therapeutic efficacy of drug, but also to determine whether the patients are likely to respond to a therapy. To achieve these goals, a variety of imaging techniques have been used, including near-infrared fluorescent (NIRF) imaging, magnetic resonance imaging (MRI) and nuclear imaging (SPECT and PET). It has shown that the combination of different imaging modalities can offer synergistic advantages to facilitate biodistrubtion analysis with more detailed information of diseased sites. This presentation will highlight our recent advances that have been made in the development of multifunctional nanoparticles and the applications of these nanoparticles into theragnostic nanomedicine