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Microneedles: Fundamentals and Biomedical Applications

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영어

A microneedle is a three-dimensional (3D) micromechanical structure and has been in the spotlight recently as a drug delivery system (DDS) as well as blood extraction device for ubiquitous healthcare system. Various types of microneedles have been fabricated using subtractive micromanufacturing methods which are based on the inherently planar two-dimensional (2D) geometries. However, traditional subtractive processes are limited for flexible structural microneedles and makes functional biomedical applications for efficient drug delivery and blood sampling difficult. The authors of the present study propose drawing lithography as a unique additive process for the fabrication of a microneedle directly from 2D planar substrates, thus overcoming a subtractive process shortcoming. The present presentation provides the overview of the principal drawing lithography technology and its biomedical applications.[1]

저자정보

  • Hyungil Jung Department of Biotechnology, Yonsei University
  • Chang Yeol Lee Department of Biotechnology, Yonsei University
  • Cheng Guo Li Department of Biotechnology, Yonsei University
  • Huisuk Yang Department of Biotechnology, Yonsei University

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