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Biotechnological production of human milk oligosaccharides

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Human milk contains a large variety of oligosaccharides (HMOs) that have the potential to modulate the gut flora, affect different gastrointestinal functions, and influence inflammatory processes. This review introduces the recent advances in the microbial and coupled enzymatic methods to produce HMOs with grouping them into trisaccharides (sialyllactose and fucosyllactose) and complex oligosaccharides (lacto-Nbiosederivatives). Particularly, a whole cell biosynthesis of fucosyllactose by using recombinant Escherichia coli isr egarded as a promising method.

저자정보

  • Nam Soo Han Department of Food Science and Technology, Chungbuk National University
  • Jin-Ho Seo Department of Agriculture Biotechnology, Seoul National University

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