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The purpose of this study is to investigate effects of social dance program on the mental health with serotonin and growth hormone for youth shelter in adolescents The subjects were randomly divided into two groups; Youth shelter (N=11) and normal adolescents(N=10) group. Mental Health with serotonine and growth horomone were measured pro and post program. The results pro program is youth shelter in Adolescents were showed significantly changes of Mental health. In Social dance program, there showed were significance Mental health factor in depression(p=.003), anger (p=.006), vigor(p=.001) on groups. In serotonin and growth hormone, there showed were significance on groups. but, post program were significance (p<.001) on time in All groups. That the combined serotonin ware positively relate to Mental health factor in vioge and combined growth hormone ware positively relate to Mental health factor in vioge and depreeion.