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Purpose： The aims of this study was to identify changes mu rhythm according to familiarity with a stimulus in people with stroke.
Methods： Seventeen right-handed participants were asked to observe 2 different stimulus; a non-familiarity stimulus condition (NFSC), and a familiarity stimulus condition (FSC). Electroencephalogram (EEG) signals from electrodes on the participant`s scalp were recorded during action observation. The activation of the mirror neuron system was compaired between FSC and NFSC by a paired t-test. An independent t-test was used to compare the difference between right and left hemispheres for the activation of the mirror neuron system during action observation of performing a task with the right hand.
Results： The result of paired t-test showed no significantly difference between NFSC and FSC in the activation of the mirror neuron system. The Result of independent t-test also showed no significantly difference in the activation of mirror neuron system between the right and left hemispheres.
Conclusion： The familiarity with a stimulus had no signigicant effect on the activation of the mirror neuron system according to the familiarity and in either the right or left hemispheres in people with chronic stroke.