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Screening of a new mushroom having xanthine oxidase inhibitory activity for development of new anti-gout agent

초록

영어

This study was carried out to obtain new anti-gout agent from mushrooms. Various extracts from twelve kinds of mushrooms were prepared by water and ethanol extractions and its anti-gout xanthine oxidase inhibitory activity were investigated. Water extract of Flammulina velutipes and Agaricus bisporus fruiting bodies showed high xanthine oxidase inhibitory activity of 70.8% and 60.0%, respectively. However, its inhibitory activity of these ethanol extracts were very low excepet 60.3% of Innotus obliquus. Finally, we selected Flammulina velutipes, showing the highest xanthine oxidase inhibitory activity as a producer of new anti-gout agent.

저자정보

  • Jung-Hwa Song Department of Life Science and Genetic Engineering, Paichai University, Daejeon 302-735, Korea
  • Bolormaa Zanabaatar Department of Life Science and Genetic Engineering, Paichai University, Daejeon 302-735, Korea
  • Jeong-Hoon Jang Department of Life Science and Genetic Engineering, Paichai University, Daejeon 302-735, Korea
  • Hyung-Jun Noh National Institute of Agricultural Science and Technology, Suwon 441-707, Korea
  • Young-Bok Yoo National Institute of Agricultural Science and Technology, Suwon 441-707, Korea
  • Jong-Soo Lee Department of Life Science and Genetic Engineering, Paichai University, Daejeon 302-735, Korea

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