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Poster-13

Glycosylation of free sterol by whole-cell bioconversion in E. coli

초록

영어

Steryl glucosides play important roles in many physiological and biochemical process in organism such as the heat shock, enhancement of immunological system, etc. The alignment of a putative sterol glucosides isolated from S. tropica CNB-440 has been shown 34%, 42% and 57% in homology with the corresponding ones from Arabidopis thaliana, Avena sativa and Salinispora arenicola CNS-205, respectively. Engineered E. coli host-high level production of the UDP-glucose was used for whole-cell bioconversion of free sterol (cholesterol and β-sistosterol) and the production of glycosylated product was only detected with β-sitosterol as substrate.

저자정보

  • Jae Kyung Sohng Institute of Biomolecule Reconstruction, Department of Pharmaceutical Engineering, Sun Moon University
  • Jae Kyung Sohng Institute of Biomolecule Reconstruction, Department of Pharmaceutical Engineering, Sun Moon University

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