earticle

영어

Mainly, chemical and physical methods have been used for immobilization of bioactive materials. However, there are some of drawbacks with those methods. For example, chemical method may produce potential toxic by-product and, in case of physical method, low efficiency of immobilized bioactive material is observed. To solve these problems, recently, the immobilization by photoreaction has been researched widely. The advantages of photo-immobilization are 1) high selectivity of chemical reactions or processes under mild conditions (ambient temperature of also much below), 2) typically no need for added catalysts or special solvents, 3) spatially addressable effects (2D and 3D structuring possible) and 4) applicable to very small and (relatively) large scales. To use for photo-immobilization, various natural polymers reacted by irradiation to ultra violet and visible light can be synthesized. It is considered that these photoreactive natural polymers can be applied for medical area to increase biocompatibility and functionality, for example, coating agent for bioinnert devices like stent and implant, anti-adhesive agent, wound dressing and bio-adhesive.