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논문검색

Poster-10

Plant made pharmaceuticals (PMP) as a convenient, safe and economical alternative to the shortfall

초록

영어

Since the completion of the human genome project, development of new therapeutic and diagnostic proteins have been exponentially increased, but widespread use of these molecules has been hampered by production bottlenecks such as low yields, poor and inconsistent product quality and a shortage of production capacity. Especially, we are facing a growing demand for protein diagnostics and therapeutics, but lack the capacity to meet those demands using established facilities. Over the last decade, plants have emerged as a convenient, safe and economical alternative to mainstream expression systems which are based on the large-scale culture of microbes or animal cells, or transgenic animals. The production of plant-made pharmaceuticals and technical proteins is known as Molecular Farming. The objective is to harness the power of agriculture to cultivate and harvest plants or plant cells producing recombinant therapeutics, diagnostics, industrial enzymes and green chemicals. Molecular Farming has the potential to provide virtually unlimited quantities of recombinant antibodies, vaccines, blood substitutes, growth factors, cytokines and enzymes for use as diagnostic and therapeutic tools in health care, the life sciences and the chemical industry. The overall aim of our research is to develop new plant molecular farming systems which are economic, efficient, stable and safe. To accomplish the purpose, we are performing specific research objectives in regards to plant molecular farming.

저자정보

  • Wahyu Indra Fanata Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University
  • In Jung Jung Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University
  • Bo Hwa Son Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University
  • Jae Yong Yoo Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University
  • Je Hein Kim Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University
  • Rikno Harmoko Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University
  • Ki Seong Ko Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University
  • Sang Yeol Lee Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University
  • Kyun Oh Lee Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University

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