earticle

영어

Surface (or biosurface) organic chemistry is an emerging research field in organic chemistry, the ultimate goal of which is to control the interfaces between biological and non-biological systems at the molecular level for the fundamental understanding of biological interactions at interfaces and for the potential applications to (nano)biotechnology and biomedical sciences. The term, “biosurface”, implies that the field focuses on surfaces (or interfaces in general) and the surfaces are functional in the interactions with biological entities, such as biomolecules (DNAs, proteins, and polysaccharides) and cells. The biological interactions would occur at nonbiological (in other words, man-made) surfaces via either organic or inorganic functionalities, and in the field of biosurface organic chemistry, organic functional groups are designed and introduced onto man-made surfaces to control the biological interactions. Biosurface organic chemistry is composed of three mutually interacting research fields: surface organic chemistry, bioconjugation, and micro/nanofabrication. One of the aims of surface organic chemistry is to control the physicochemical properties of man-made surfaces by the functionalization of surfaces, yielding “tailor-made” surfaces. The tailor-made surfaces could be either “static”, playing any designated roles, or “dynamic”, playing switchable roles in response to demands. In this talk, I will present some of research results in the field of biosurface organic chemistry. Because of the wide use of self-assembled monolayers (SAMs) in surface sciences and technologies, a large portion of the review contains research results based on SAMs.