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Purpose: This study is the narrative investigating research to comprehend the climacteric symptoms, depression and health promoting behavior of the male workers and to develop the nursing intervention. Methods: The research was done from August to September 2011, and the subjects were the middle-aged males between 40 and 64 working in capital cities of Chungcheongnamdo. Among the 220 questionnaires, 189 were retrieved and used for the analysis. The data analysis was done by x2-test, and t-test using the SPSS/WIN 19.0 program. Results: The 70.9% of the subjects showed male climacterium and among them, those in their 40s showed high rate to the change in the body and emotions whereas those in their 50s showed high rate to the sexual function-related symptoms. Also, having the climacteric symptoms showed significant changes in depression and health promoting behavior. Conclusion: To promote health of the middle-aged male workers and the nursing intervention for those who show depression, verifying whether these males have climacteric symptoms is necessary.