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논문검색

Characterization of Quantitative Trait Loci (QTL) for Growth using Genome Scanning in Korean Native Pig

초록

영어

Molecular genetic markers were genotyped used to detect chromosomal regions which contain economically important traits such as growth traits in pigs. Three generation resource population was constructed from a cross between the Korean native boars and Landrace sows. A total of 193 F2 animals from intercross of F1 were produced. Phenotypic data on 7 traits, birth weight, body weight at 3, 5, 12, 30 weeks of age, live empty weight were collected for F2 animals. Animals including grandparents (F0), parents (F1), offspring (F2) were genotyped for 194 microsatellite markers covering from chromosome 1 to 18. Quantitative trait locus analyses were performed using interval mapping by regression under line-cross model. To characterize presence of imprinting, genetic full model in which dominance, additive and imprinting effect were included was fitted in this analysis. Significance thresholds were determined by permutation test. Using imprinting full model, four QTL with expression of imprinted effect were detected at 5% chromosome-wide significance level for growth traits on chromosome 1, 5, 7, 13, 14, and 16.

목차

INTRODUCTION
 MATERIAL & METHODS
  Experimantal population and performance traits
  DNA, isolation, marker selection and genotyping
  Statistical Analysis
 RESULT AND DISCUSSION
 REFERENCES

저자정보

  • Lee, H. K. Genomic Informatics Center, Hankyong National University
  • I. S. Choi Department of Bionolgy Genomic Engineering, Hankyong National University
  • B. H. Choi Genomic Informatics Center, Hankyong National University
  • T. H. Kim Genomic Informatics Center, Hankyong National University
  • I. J. Jung Genomic Informatics Center, Hankyong National University

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