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Purpose: This study was carried out in order to examine the relationship of job satisfaction and quality of life on the dental technicians and to analyze its influence. Methods: A self-reported questionnaire survey was carried out by having convenience sampling as 220 dental technicians who work in Seoul Metropolis, Gyeonggi-do Province, Daejeon and Chungnam Province from March 12, 2012 to April 13. A research tool was used questionnaire that was proved reliability and validity. It was prepared with totally 50 questions such as 12 items for subjects’ general characteristics, 18 items for job satisfaction measurement, and 20 items for life quality measurement. An analysis of the collected data was computationally processed by using SPSS Win 17.0 program. An analytical technique was made by using statistical techniques such as frequency & percentage, T-test or One-way ANOVA analysis. The following are the analytical results of the collected materials. Results: As a result of analyzing research subjects’ job satisfaction level, there was significant difference(P<0.05) in items of religion, hobby life, working environment, and rest time out of daily work. The whole mean in job satisfaction was indicated to be relatively high with 3.13. However, job satisfaction with social recognition, salary, and safety was indicated lowly. As a result of analyzing research subjects’ life quality level, there was significant difference(P<0.05) in items of religion, hobby life, working environment, and rest time out of daily work. The whole mean in quality of life was indicated to be relatively high with 3.10. However, the satisfaction was indicated lowly in the whole life quality and the life environment sphere. As a result of analyzing correlation between job satisfaction and life quality, all variables were indicated to be positive correlation in high significance level, thereby having been indicated that the higher job satisfaction leads to the higher life quality. Conclusion: As a result of research, the dental technicians’ job satisfaction was indicated to have high correlation with quality of life. An effort is judged to be necessary for establishing fair compensation system, improving welfare policy and enhancing social recognition and position in order to promote dental technicians’ quality of life.