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Purpose: The purpose of this study was to investigate the relationship of psychiatric and community mental health nurses' job satisfaction. Methods: This was a descriptive and correlational study in which 151 psychiatric and community mental health nurses (PCMHNs) took part between September and October 2009. Results: The mean score for job satisfaction of the participants was 3.25. In job satisfaction, there were significant differences between psychiatric and community mental health nurse practitioner (PCMHNP) and nurse in community mental health center. All variables except role conflict were positively correlated with job satisfaction. As a result, factors influencing job satisfaction were reward system (β=.46, p<.001), self-esteem (β=.35, p<.001), leadership (β= .27, p<.001), career as a PCMHNP (β=-.12, p<.007), job-related characteristics (β =.11, p<.24), and career as a nurse in community mental health center (β=.09. p<.045). These factors explained 70.3% of the total variance. Conclusion: The results indicated that the comprehensive understanding of job satisfaction to the independent variables could suggest the way how to increase the job satisfaction for psychiatric and community mental health nurse who are a catalysts promoting mental health in community mental health center.