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외상성 부종에 대한 데옥시리보뉴클레아제-브로멜라인정의 유효성 및 안정성 평가를 위한 제IV상 임상시험

원문정보

Phase IV Clinical Trial, the Evaluation of Efficacy and Safety of Deoxyribonuclease-Bromelain Tablet in Patients with Traumatic Edema

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There was clinical study to support the efficacy that the anti-inflammatory and analgesic properties of deoxyribonuclease, bromelain helped to reduce symptoms of inflammation. The current study investigated the effects of deoxyribonuclease, bromelain on local traumatic edema. The author used a drug containing proteolytic and mucolytic enzymes, deoxyribonuclease and bromelain, into 61 patients from 16 to 89 years old. The therapeutic response and tolerance had been excellent, which was permitted to a swift resolution on local traumatic edema and a prompt functional reestablishment. These results demonstrated that the drug was effective in local edema symptoms, pains and improving general condition suffering from trauma. Consequently, the use of the proteolytic and mucolytic enzyme require improvement in the rehabilitation of the injured.

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