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Regiospecific Ring-Opening of Unsymmetrical Epoxides to the Corresponding Less Substituted Alcohols by Newly-Devised Meerwein-Ponndorf-Verley Type Reagents

원문정보

Jin Soon Cha

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초록

영어

A newly-devised Meerwein-Ponndorf-Verley (MPV) reagents, such as diisobutylacetoxyalanes and diisobutylmethanesulfonylalanes, achieved a clean conversion of unsymmetrical epoxides to the corresponding less substituted alcohols. This review covers the recent developments for such a regiospecific ring-opening reaction of epoxides.

목차

Abstract
 1. Introduction
 2. Mechanistic Consideration of the MPV Reactions
  2.1. Aluminum Reagents
  2.2. Boron Reagents
  2.3. Appearance of New MPV Type Reagents
  2.4. Auminum – Containing Reagents
  2.5. Boron – Containing Reagents
  2.6. Application for Organic Synthesis
  2.7. General Reducing Characteristics of Diisobutylaluminum and Diisopinocampheylboron Derivatives Toward Common Organic Functional Groups
  2.8. Regioselective Ring-opening of Epoxide
 3. Concluding Remarks
 References

저자정보

  • Jin Soon Cha Department of Chemistry, Yeungnam University, Gyongsan 712-749, Korea

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