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In this study, the self-based survey was conducted with 225 dental staffs employed by the clinics, general hospitals and university hospitals in Busan and Gyeongsangnam -do. With SPSS Win. 19.0, frequency analysis, descriptive statistics, cross-tabulations, and multiple regression analysis were performed on the collected data. The results were as follows: 1. In frequency analysis of interest in the infection control, analysis factor of respondents in dental hospitals is 58.2 percent, higher than the dental clinics 2. The order in which the average of the practice of dental practitioners appear: sterilization & disinfection, personal hygiene, personal protective methods, asepsis, medical waste management. 3. Influence was investigated that high interest of co-workers or high interest of dentist or training of dental infection or high patient needs personal hygiene to personal hygiene of sub-area dental infection control practice 4. Influence was investigated that not being around cleaners or training of dental infection to personal protection methods of sub-area dental infection control practice. 5. Influence was investigated that high interest of co-workers or high interest of dentist to asepsis of sub-area dental infection control practice. 6. Influence was investigated that working in dental hospital or high interest of dentist to sterilization & disinfection of sub-area dental infection control practice. Putting above results together, we can confirm that ongoing commitment and perceptions about infection control of dental office are changing, and recognition and practice of infection control are going on well in dental hospitals employing many doctors and staffs. Therefore, we conclude that constant attention and training are required in dental clinics, and non-continuous interest and research are performed for further promotion and development.