earticle

영어

Fluorescence polymers have received a great deal of interest due to their unique physical properties such as conductivity, electroluminescence. Moreover, polyphenylenevinylene (PPV) and their derivatives are currently the most popular class of conjugated polymers used in electronic materials, such as organic light-emitting diodes (OLEDs). Hybrid nanomaterials containing two or more functionalities have been received attention as attractive candidates for biomedical application. Furthermore, superparamagnetic iron oxide (Fe3O4) nanoparticles have been extensively studied for use as magnetic resonance imaging (MRI) contrast agents. In this study, we prepared multifunctional nanoparticles incorporating fluorescent polymer and Fe3O4 nanoparticles, and coated by ionic polymer layers. Properties of prepared multifunctional nanoparticles were characterized by transmission electron microscopy (TEM) and particle analyzer, UV spectrometer and PL spectrometer. The bioapplication of nanoparticles was evaluated by specific binding capability, cell permeability and viability by optical and MR imaging. Consequently, we expect that our nanoparticles will have considerable potential as a powerful novel material within the emerging field of biomedical, such as drug delivery, therapeutics and magnetic resonance imaging (MRI) contrast agents.