earticle

영어

We developed a biomemory device with enhanced signal which consists of heterolayers of cysteine-modified azurin/gold nano particle (Az/GNP). The cysteine residues that were attached onto azurin proteins were introduced via site-directed mutagenesis method (SDM) and the purpose was to effectively immobilize the modified azurin onto gold surface. Then gold nanoparticles of 5nm size were adsorbed onto the self-assembled azurin layer. The atomic force microscopy (AFM) and surface plasmon resonance (SPR) were used to investigate the fabricated Az/GNP bilayer. Also, cyclic voltammetry (CV) was employed to confirm the amplified electrochemical signal. As a result, we obtained two redox potentials and with these parameters, using chronoamperometry (CA), function of biomemory device was verified. If foretold biomemory device could be developed in molecular size, it would be able to replace the existing silicon based memory devices in the near future.