earticle

영어

Magnetic beads modified with DNA intercalating agents have been developed for simple separation of DNA in solution after PCR by Microwave reactor. It is widely reported that a microwave system could enhance the chemical and biological reactions. An uniform type of microwave system for biological and mild chemical reaction has been developed and applied for a synthetic and some enzymatic reactions. In this study, We modified the bare magnetic particle to 9-aminoacridine coated magnetic particle using conventional method and microwave assisted method. As a result, we confirm, when we reacted with microwave systems, that 9-aminoacridine coated magnetic was increased reaction efficiency in short time(<30min). We developed and confirmed the microwave system that increases the reaction efficiency of surface modification on magnetic particles and shortens the time for reaction.