원문정보
초록
영어
b-glucans are structural cell wall polymers of many microorganisms which possess several dunctionality including antioxidant activity and immunomodulatory properties. In the previous study, the low molecular weight b-glucans degraded by gamma irradiation showed higher antioxidant. In this study, it has been carried out to evaluate the immune-enhancing activities of low molecular weight b-glucan degraded by gamma irradiation. The results showed that RAW264.7 macrophage cell stimulation activities of low molecular weight b-glucan were higher than that of high molecular b-glucan. In addition, the oral administration of low molecular weight b-glucan significantly increased the proliferation and cytokine (IFN-ɤ and IL-2) release of spleen and Peyer’s patch cells compared with high molecular weight b-glucan.