earticle

영어

Byssal cuticles are compelling paradigms as wear and damage resistant coatings for compliant materials. The byssus of Mytilus species are covered by the protective coating protein Mytilus edulis foot protein-1 (Mefp-1). Protective coatings for tissues and materias are appealing to medical implant materials. The hardness(~ 2 GPa) and stiffness(~ 0.1 GPa) of the coating measured by nanoindentation are comparable with those of robust engineered epoxy, but the ultimate strain of the Mytilus cuticles are 20 times higher than that of expoxy.The main challenge in these bio-mimetic approaches is to sufficiently simplify the structure to enable easy-to-use synthesis routs. We produced, purified recombinant mussel foot protein-1 (Rmfp-1) for mimicking the byssal coating protein mefp-1. Rmfp-1 was produced from E.coli. Decapeptide was produced by cutting the Rmfp-1. The properties of Rmfp-1 and decapeptide were directly measured at the nano-scale by using the Surface Force Apparatus (SFA)