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논문검색

식품의약품안전청에 보고된 심혈관계 약물유해반응의 특성 분석

원문정보

Characteristics of Cardiovascular Adverse Drug Reactions Reported to KFDA

유기연, 조혜경, 이숙향

피인용수 : 0(자료제공 : 네이버학술정보)

초록

영어

Adverse drug reaction (ADR) is a global problem of major concern in health care. ADRs can be accrued in any organs or systems. However, cardiovascular ADRs could be a more serious problem if they are irreversible or severe. For this reason, this study was conducted to analyze pattern and severity of cardiovascular ADRs, and suspicious medication. Total 646 reports including cardiovascular ADRs reported to the KFDA between January and June 2010 were analyzed. Amlodipine besylate (36 reports, 3.3%), iopromide (29 reports, 2.7%), tramadol HCl (28 reports, 2.6%) were most suspicious drugs that occurred cardiovascular ADRs. The most common cardiovascular ADRs were hypotension( 236 reports, 33.1%), palpitation (134 reports, 18.8%), and hypertension (89 reports, 12.5%). The most frequent ADRs were occurred in the age group of more than 60. This result could be of help to prescribers and other healthcare providers to predict and prevent cardiovascular ADRs. Also this study suggested that patients with cardiovascular ADR risk factors should be intensively monitored during the medications

목차

Abstract
 연구 방법
  분석대상 자료
  의심되는 약물의 종류
  약물유해반응의 종류
  약물유해반응의 중증도
  환자의 나이
  약물유해반응 보고자
 연구 결과
  심혈관계 ADR 원인으로 의심되는 약물의 종류
  심혈관계 ADR의 종류
  연령에 따른 심혈관계 ADR
  성별에 따른 심혈관계 ADR
  보고자 특성에 따른 심혈관계 ADR
 고찰
 참고문헌

저자정보

  • 유기연 Ki Yon Rhew. 동덕여자대학교 약학대학
  • 조혜경 Hea-Kyoung Cho. 한국 BMS 제약
  • 이숙향 Sukhyang Lee. 아주대학교 약학대학

참고문헌

자료제공 : 네이버학술정보

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